XCell ATF System: Scaling Upstream Bioprocessing with Perfusion Efficiency

Published on Repligen Brochure (Nov 2024)

Repligen’s XCell ATF System brings upstream process intensification to life by enabling continuous bioprocessing with longer run times, reduced energy use, and viable cell densities over 100 million cells/mL. By applying alternating tangential flow (ATF) through single-use or stainless steel filters, this system reduces fouling and supports scalable perfusion from 0.5 L to 5000 L. Proven across monoclonal antibodies, vaccines, and recombinant proteins, it offers a viable path to 20x higher yields with a smaller facility footprint and lower COGS.

Read the full brochure via Repligen:

👉 XCell ATF System Brochure (PDF)

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