Stem Cell Discovery Could Transform Bone Fracture Healing

Published on: Penn Medicine

Researchers at the University of Pennsylvania have identified a muscle-derived stem cell, Prg4+, that can transform into bone-forming cells and accelerate fracture repair. In mouse studies, these cells migrated to injury sites, producing all cell types needed for bone healing. The findings open new pathways for treating catastrophic injuries and could improve recovery in older adults or those with muscle loss.

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