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First MS Patient Receives ‘Off-the-Shelf’ CAR T-Cell Therapy

Updated: Aug 14

Published on: Multiple Sclerosis News Today


A U.S. trial has treated the first multiple sclerosis (MS) patient with azercabtagene zapreleucel, an “off-the-shelf” CAR T-cell therapy made from healthy donor cells. The approach targets CD19 on B-cells to reduce inflammation and nerve damage. This Phase 1 study aims to assess safety and potential to slow disability progression in progressive MS.



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