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First Gene-Edited Islet Cell Transplant Shows Success in Diabetes

Published on: ScienceAlert


For the first time, a type 1 diabetes patient has begun producing insulin after receiving gene-edited islet cells that avoid immune rejection without the need for immunosuppressant drugs. The cells, modified with CRISPR and injected into the patient’s forearm muscle, responded to glucose levels for 12 weeks. This proof-of-concept, reported in The New England Journal of Medicine, marks a major step toward safer and more effective diabetes cell therapies.



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